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Hi, who funded this small study? I looked for supplements that support this. Lo and behold one company in England produces this. The cost is just under $64 per month- $760 per year - outrageous! This is the third study that has one company selling the exact formula used in the study. An Italian company on their website discussed paying for the study. I don’t see that here.

Can a generalized prebiotic containing that type (but not specific number) be helpful?

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Jun 20·edited Jun 20Author

Hi Susan, I'm afraid I'm not familiar with what probiotics are available in the US. You could also look out for 1 billion written as 1 x 10^9, or find one that contains more than 1 billion. If a probiotic containing multiple strains of bacteria, that includes B. longum 1714 at that dose, then that could be an option too. Though when there's multiple strains we don't know how they interact with each other and what collective effect they then have, as usually research has been done on one strain, or two strains together rather than multiple.

The first two studies Alimentary Health provided the placebo and the probiotic containing the B. longum 1714 strain used in the research, and their technical director was on the author list, but did not fund the study.

The third study seems at least partly funded by Novonesis/PrecisionBiotics, and has multiple authors from the company on the author list.

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Hi, the supplements pictured in the blog do not contain the correct b. Longum. I found Microbiome Labs on amazon for the price listed above and an internet search found precision biotics in the UK with a similar charge. That’s all I could find. I’m cynical in that I suspect these studies are just a marketing ploy - they may help a lot of people, but the driving motivation is making money by charging massive amounts. How does that help a huge population in need?

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Jun 20·edited Jun 20Author

Hi Susan, the picture in the newsletter is a stock photo of a probiotic supplement. I'm sorry you haven't had much luck finding it in the US - frustrating! While we do need to carefully consider industry funding in research, that doesn't mean that studies that have had probiotics supplied free of charge, or that are entirely industry funded, aren't responsibly and ethically researched. Two of the studies I included above are published in Nature, one of the best peer-reviewed journals. I'm careful about which studies I include. Industry funded research that we do need to be careful of are those that are badly designed studies with the intent to get the outcome they want - though they are few and far between. Many top quality research institutions would not be able to survive if they didn't have industry funding, with the companies having no involvement in the research itself. When it comes to probiotics - this is still an early field of research, we only had the technology to start exploring the microbiome in depth 20 years ago!

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deletedJun 19
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If you google search the DOI I shared below the paper will come up. The covid vaccine is still the safest most reliable way to build protection against COVID-19 infection, and helps to ensure that COVID-19 doesn't progress into a serious long-term illness.

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deletedJun 19
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Hi Ki, research has actually showed the opposite - that there's minimal, if any, shift in microbiome composition from the covid vaccine (assume this is the vaccine you are referring to) whereas there are significant shifts with a covid infection DOI: 10.26508/lsa.202302529

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